There are a few jobs in the studio I try to avoid at all costs. High on the list is transferring heddles from one shaft to another. This is such a hated task that I tend to design for whatever number of heddles is installed on any given loom. My looms are generally set up with an equal number of heddles on all shafts.
Here's a draft I came up with in order to use roughly the same number of heddles on each shaft. It's a lampas with plain weave as the primary cloth, threaded on shafts 7-16, and 3-end (jeans) twill as the secondary cloth, threaded on shafts 1-6. I could have restricted secondary ends to shafts 1-3 and put primary ends on shafts 4-16, giving me more patterning scope, but that would have thrown the heddle count out of balance. Am I crazy? Maybe, but avoiding the transference of heddles was my major goal.